New research paper from international scientist puts 150-year ceiling on human life

Unless your name is Vlad Dracula, discovered the Holy Grail, or recently stumbled upon the legendary Fountain of Youth, any idea of ​​living forever is likely to remain a fanciful illusion, as a new research paper has put a term to human longevity. to 150 as the extreme limit.

This new study, recently presented to the online journal Nature Communications by Singapore-based biotechnology company Gero, Roswell Park Comprehensive Cancer Center in Buffalo, New York, and the Kurchatov Institute in Moscow, details how humans have the ability biological to live 120-150 years as “absolute limit”.

According to their semi-depressing findings, the researchers used mathematical modeling to predict that once the body clock stops at around 150, our bodies lose their ability to bounce back from any kind of trauma, stress, or stress. disease, which leads to your ultimate demise.

“Studies like this are based on historical and current population data,” Judith Campisi, a professor at the Buck Institute for Research on Aging in Novato, Calif., Who was not part of the study, told Live Science. “It’s a guess, but based on good numbers.”

Comprehensive data sets including anonymous medical records and blood tests for more than 500,000 people have been drafted from the US, UK and Russia to compile the team’s alarming statistics. Studies of this nature, those which may not fully take into account a person’s lifestyle, income, socioeconomic status, exercise, and diet, are only used as a guide. and often tend to be inaccurate.

The researchers targeted two specific numbers obtained from blood tests for three different age groups: a ratio of two types of disease-fighting white blood cells; and a measure of the variability in the size of red blood cells.

“Just as a person can have grayer hair as they age, both of these numbers increase with age,” said Dr. Marc J. Kahn, dean of the Kirk Kerkorian School of Medicine University of Nevada in Las Vegas, who does was not on board the study. “Scientists call these biomarkers of aging.”

After taking the blood test results, they then fed the data into a computer model to come up with something the team calls the “dynamic organism state indicator” (DOSI), which is basically a a measure of “biological age” which quantifies how well a person can recover from stressors such as illness or injury.

“The authors are able to use this DOSI… to measure recovery time,” Kahn noted. “The problem is that at some point in aging, the recovery time is so long that we lose resilience.”

Scientists involved in the study included data regarding exercise and physical activity levels, recorded as the number of steps taken per day, as another piece of validation. As you might expect, younger people are generally much more active than those of an older age. Just because you have the capacity to exist on Earth until the ripe old age of 150 does not necessarily mean that those years would have a corresponding quality.

“This has huge societal implications, far more than the maximum lifespan,” Campisi said.

Resilience in old age appears to be the key to prolonging life, and scientists believe that if resilience can be strengthened, a person’s health over decades would follow. Science fiction-like inventions like mechanical organs and reprogrammed cell therapies could help add years to human existence.

“Now we’re talking about the whole concept of human and mechanical constructions that are hallmarks of science fiction,” Kahn explained. “It’s really going to take this stuff to expand the human [life span]. “

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